About the Registry

Multiple sclerosis (MS) is one of the most common inflammatory demyelinating disease of the Central Nervous System (CNS) and is generally believed to be autoimmune in origin. Although exact prevalence in India is not well known, it is estimated to be anything between 20-40/100,000. Other allied demyelinating disorders in the continuum of MS include Neuromyelitis Optica spectrum disorder (NMOSD), myelin oligodendrocyte glycoprotein antibody (MOG) associated disease, optic neuritis (ON) alone or as a part of MS, NMOSD, MOG and acute disseminated encephalomyelitis (ADEM).

The IMSRN will be the first Indian nationwide database of MS and allied demyelinating disorders and the first dedicated expert research network focusing on these disorders. This will cerate an organized system for the data collection, storage, retrieval, analysis, and dissemination of information on MS

26
SITES

PATIENTS

CITIES

STATES

Potential Data Cohorts

DMT Cohort

Details of treatment will help understand the response to therapy, switching, escalation and adverse effects.

Biomarker Cohort

Biomarker samples collected from MS subjects will aid in understanding disease association, behavior, diagnosis and prognosis.

Pregnancy Cohort

The information collected on women with MS will help study outcomes during and after pregnancy.

Imaging Cohort

The neuroimaging data will help guide diagnostic and prognostic information.

Many Facets of IMSRN

This registry and network would encompass various elements including demographic data, clinical behavior, risk factors, therapeutic response, imaging patterns, basic research, clinical research, etc. There will be an integration of all these elements to comprehensively focus on these disorders and help us understand them better.